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Keywords: intestinal microbiome, elderly, newborns, dietary intervention, probiotics. ADULTS The human gut microbiota reaches its maximum complexity at adolescence following a gradual increase in the phylogenetic diversity of the microbiome during adulthood. Table 1 Main targets for nutritional intervention in order to restore a balanced microbiota at extreme ages of life.

Open in a separate window. Conflict of Interest Statement The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The placenta harbors a unique microbiome. Establishment of the gut microbiota in Western infants. Acta Paediatr. Anaerobe 18 — Establishment and development of intestinal microbiota in preterm neonates. FEMS Microbiol. Development of probiotic products for nutritional requirements of specific human populations.

Life Sci. Facultative to strict anaerobes ratio in the preterm infant microbiota: a target for intervention? Gut Microbes 3 — Assessment of intestinal microbiota modulation ability of Bifidobacterium strains in in vitro fecal batch cultures from preterm neonates.

Anaerobe 19 9—16 Enterotypes of the human gut microbiome. Nature — Gut microbiota of healthy Canadian infants: profiles by mode of delivery and infant diet at 4 months. CMAJ — The individual-specific and diverse nature of the preterm infant microbiota.

Fetal Neonatal Ed. Assessment of the global intelligence and selective cognitive capacities in preterm 8-year-old children. Psicothema 22 — Probiotic supplementation in mothers of very low birth weight infants. Establishment of intestinal microbiota during early life: a longitudinal, explorative study of a large cohort of Danish infants.

Microbiota profile in feces of breast- and formula-fed newborns by using fluorescence in situ hybridization FISH. Anaerobe 17 — Aging of the human metaorganism: the microbial counterpart. Age Dordr. Ageing and gut microbes: perspectives for health maintenance and longevity. Mode of delivery affects the bacterial community in the newborn gut.

Human milk oligosaccharides: every baby needs a sugar mama. Glycobiology 22 — Microbiota and neurodevelopmental windows: implications for brain disorders. Trends Mol. Epigenetic mechanisms elicited by nutrition in early life. Composition, variability, and temporal stability of the intestinal microbiota of the elderly. Gut microbiota composition correlates with diet and health in the elderly. Dietary intervention impact on gut microbial gene richness.

High-fat diet alters gut microbiota physiology in mice. ISME J. Diversity of microbes in amniotic fluid. Fetal Neonatal Med. Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns.

Probiotics and prebiotics and health in ageing populations. Maturitas 75 44—50 Diversity of the human intestinal microbial flora. Science — Fecal enema as an adjunct in the treatment of pseudomembranous enterocolitis. Surgery 44 — The gut microbiota and mucosal homeostasis: colonized at birth or at adulthood, does it matter? Gut Microbes 4 — Development and validation of a microarray for the investigation of the CAZymes encoded by the human gut microbiome.

Determinants of the human infant intestinal microbiota after the introduction of first complementary foods in infant samples from five European centres. Microbiology — Intestinal microbiota of 6-week-old infants across Europe: geographic influence beyond delivery mode, breast-feeding, and antibiotics. Impact of diet in shaping gut microbiota revealed by a comparative study in infants during the six months of life. Intestinal microflora in early infancy: composition and development.

Composition of the early intestinal microbiota: knowledge, knowledge gaps and the use of high-throughput sequencing to address these gaps. Relating the metatranscriptome and metagenome of the human gut. Probiotics and Gut-Brain Axis: promising area in well-being. Agro Food Ind. Hi Tech 24 6—9. Cesarean delivery is associated with an increased risk of obesity in adulthood in a Brazilian birth cohort study. Fatty acids intake and immune parameters in the elderly.

Metatranscriptomic approach to analyze the functional human gut microbiota. The impact of perinatal probiotic intervention on gut microbiota: double-blind placebo-controlled trials in Finland and Germany. Anaerobe 18 7—13 Immunosenescence: influenza vaccination and the elderly. The differences in colonic mucosal microbiota between normal individual and colon cancer patients by polymerase chain reaction-denaturing gradient gel electrophoresis.

Associations between infant feeding practice prior to six months and body mass index at six years of age. Nutrients 6 — Dynamics and clinical evolution of bacterial gut microflora in extremely premature patients. Isolation of commensal bacteria from umbilical cord blood of healthy neonates born by cesarean section. The human microbiome and its potential importance to pediatrics. Pediatrics — Functional and comparative metagenomic analysis of bile salt hydrolase activity in the human gut microbiome.

Gut metagenome in European women with normal, impaired and diabetic glucose control. Nature 99— Clostridium difficile infection in the elderly. Kanwar J. Rijeka: InTech Europe Press; , — Succession of microbial consortia in the developing infant gut microbiome. Breast- v. Prebiotics in healthy infants and children for prevention of acute infectious diseases: a systematic review and meta-analysis.

Individual genome assembly from complex community short-read metagenomic datasets. ISME J 6 — Interactions between commensal intestinal bacteria and the immune system. A metabolomic view of how the human gut microbiota impacts the host metabolome using humanized and gnotobiotic mice.

Programming infant gut microbiota: influence of dietary and environmental factors. BMC Genomics 14 Suppl. Bacterial diversity in meconium of preterm neonates and evolution of their fecal microbiota during the first month of life. Alterations in intestinal microbiota of elderly Irish subjects post-antibiotic therapy. Application of phylogenetic microarrays to interrogation of human microbiota.

Development of the human infant intestinal microbiota. PLoS Biol. Factors influencing the composition of the intestinal microbiota in early infancy. Microbiome 1 : 3 Intestinal microbiota, diet and health. A human gut microbial gene catalogue established by metagenomic sequencing.

Nature 59—65 Functional metagenomic profiling of intestinal microbiome in extreme ageing. Aging Albany N. Fecal transplantation poses dilemma for FDA. Prebiotic effects: metabolic and health benefits. Comparing microarrays and next-generation sequencing technologies for microbial ecology research.

Trends Biotechnol. Microbial targets for the development of functional foods accordingly with nutritional and immune parameters altered in the elderly. Influence of mode of delivery on gut microbiota composition in seven year old children. Gut 53 — Establishment and development of lactic acid bacteria and bifidobacteria microbiota in breast-milk and the infant gut. Anaerobe 16 — Effect of antimicrobial agents on the ecological balance of human microflora.

Lancet Infect. Influence of antibiotic exposure in the early postnatal period on the development of intestinal microbiota. FEMS Immunol. A core gut microbiome in obese and lean twins. The intestinal metabolome: an intersection between microbiota and host. Gastroenterology — Immunological hurdles of ageing: indispensable research of the human model. In addition to those already mentioned, work is being carried out on lines of research and development in the genetics of populations and prevalent diseases, in the study of somatic variation, in the application of new third generation mass sequencing technologies, and the creation of a Bioinformatic tools ecosystem for processing BigData, among others.

Product pipeline involving the assembly and subsequent sequence analysis of bacterial genomic data Ion Torrent. Data produced in the ITER mass sequencing laboratory available for direct download. Jupyter notebook integration of tools for simplified manipulation and assembly of DNA sequences. List of contributions to congresses filtered by year, and presented by researchers from ITER. Usamos cookies propias y de terceros, con la finalidad de analizar su paso por nuestra web.

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